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In the complex interaction between pathogens and the human body, antimicrobials are vital in the fight against infection. Understanding the mechanisms by which these agents combat pathogens is crucial for realising their efficacy so, how do antimicrobials work? In this blog post, we will look at the intricate mechanisms of antimicrobials with references to established research in the field. Antibiotics The majority of antimicrobials fall under the category of antibiotics, designed to combat bacterial infections.

In the complex landscape of healthcare, the effective management of antimicrobials is essential for preserving their efficacy and preventing the rise of resistant strains. Antimicrobial stewardship (AMS) programs in hospitals play a pivotal role in achieving this delicate balance. What is antimicrobial stewardship? In this blog post, we will explore the scientific foundations of AMS, its significance in healthcare settings, and the imperative for evidence-based practices. The Scientific Foundations of Antimicrobial Stewardship Understanding Antimicrobial Resistance

The issues faced by healthcare communities is ever-evolving and the rise of antimicrobial resistance (AMR) poses a formidable challenge. Antimicrobial agents are losing their effectiveness as microbes adapt and develop resistance mechanisms. In this blog post, we will explore the intricate issue of antimicrobial resistance, its implications for modern healthcare, and the strategies being employed to combat this global threat. Understanding Antimicrobial Resistance What is antimicrobial resistance? Antimicrobial resistance occurs when microorganisms, including bacteria, viruses,

What is antimicrobial? In infection prevention, antimicrobials are indispensable tools in the ongoing battle against infectious diseases. As our understanding of microbiology advances, so does the complexity of antimicrobial use and its implications. This blog post aims to provide a scientific exploration of antimicrobials, shedding light on their mechanisms, the importance of responsible use, and their critical role in infection prevention. The Basics of Antimicrobials Antimicrobials encompass a diverse range of substances designed to inhibit

As the world gradually recovers from the COVID-19 pandemic, there’s a compelling need to remain vigilant in our infection prevention and control (IP&C) practices. Research from The Times found that the recent outbreak of H5N1 bird flu in Ionia County, Michigan, has underscored this necessity. Despite its serene farmlands and peaceful pace of life, this region has become the epicentre of a new health crisis, with avian flu not only affecting birds but also cattle

Antimicrobial resistance (AMR) is a pressing global concern, and understanding how bacteria spread resistant genes is crucial in our efforts to combat this threat. In this blog post, we will delve into the scientific mechanisms that facilitate the dissemination of antimicrobial-resistant genes in bacteria. Horizontal Gene Transfer Horizontal gene transfer (HGT) stands as a cornerstone in the spread of antimicrobial resistance among bacterial populations. Three primary mechanisms underpin HGT: Conjugation: Direct Gene Exchange Conjugation involves